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Updated: May 23, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Role for the left atrial appendage occlusion device in managing thromboembolic risk in atrial fibrillation
M N Obeyesekere1, S Lockwood, P Mottram
1Monash Cardiovascular Research Centre, Monash Heart and Monash University Department of Medicine, Southern Health Network, Melbourne, Victoria, Australia. manojobey@yahoo.com
Insights
For atrial fibrillation (AF) patients, warfarin poses risks. A new percutaneous left atrial appendage (LAA) occlusion device offers an alternative to manage thromboembolic risk, especially for those unsuitable for anticoagulation.
Area of Science:
- Cardiology
- Medical Devices
- Interventional Procedures
Background:
- Warfarin therapy for atrial fibrillation (AF) is underutilized due to bleeding risks.
- Current percutaneous AF treatments do not fully address thromboembolic risk.
- Anticoagulation is crucial for preventing stroke in non-valvular AF patients.
Purpose of the Study:
- To introduce the WATCHMAN percutaneous left atrial appendage (LAA) occluder as a novel therapeutic option.
- To present the first case of LAA occlusion performed in Australia.
- To explore the methodology and potential of this new approach for thromboembolic risk management in AF.
Main Methods:
- Percutaneous implantation of the WATCHMAN device.
- Focus on left atrial appendage occlusion for stroke prevention.
- Case presentation of the procedure in an Australian patient.
Main Results:
- Successful implantation of the WATCHMAN device in the presented case.
- Demonstration of a new percutaneous method for LAA occlusion.
- Exploration of the device's role in managing thromboembolic risk.
Conclusions:
- The WATCHMAN device represents a significant therapeutic advancement for select AF patients.
- Percutaneous LAA occlusion offers an alternative to chronic anticoagulation for stroke prevention.
- This case highlights the feasibility and potential of LAA occlusion in Australia.
Abstract:
Only 50% of patients who would benefit from warfarin therapy for atrial fibrillation (AF) receive treatment because of clinical concerns regarding chronic anti-coagulation. Percutaneous strategies to treat AF, including pulmonary vein isolation with a curative intent or atrioventricular nodal ablation and implantation of a permanent pacemaker for palliative rate control, have not eliminated the need to manage thromboembolic risk. With the development of a percutaneous left atrial appendage (LAA) occlusion device (the WATCHMAN percutaneous left atrial appendage occluder - Atritech Inc., Plymouth, MN, USA) for thromboembolic protection in non-valvular AF a significant therapeutic option for select patients may be available. We present the first case performed in Australia (24 November 2009) and explore this new methodology.
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