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Updated: May 23, 2026

In Vitro Methods for Comparing Target Binding and CDC Induction Between Therapeutic Antibodies: Applications in Biosimilarity Analysis
07:25

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Published on: May 4, 2017

Efficacy of rituximab in refractory antisynthetase syndrome

V Limaye1, P Hissaria, C-L Liew

  • 1Rheumatology Department, Royal Adelaide Hospital, South Australia, Australia. vidya.limaye@health.sa.gov.au

Internal Medicine Journal
|March 22, 2012
PubMed

We report the successful use of repeated administration of rituximab in a patient with antisynthetase syndrome refractory to conventional immunosuppressive medications. A literature review revealed that previous experience with rituximab in this condition has been sparse. The rationale for the use of B-cell depleting therapies in antisynthetase syndrome has been explored in light of the current understanding of the pathogenesis of this condition.

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