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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Eczema herpeticum.

Andreas Wollenberg1

  • 1Department of Dermatology, Ludwig Maximilian University, Munich, Germany.

Chemical Immunology and Allergy
|March 22, 2012
PubMed
Summary
This summary is machine-generated.

Patients with atopic dermatitis (AD) are more prone to viral infections like herpes simplex. Eczema herpeticum, a disseminated herpes simplex virus infection, is a significant and emergent complication in AD skin lesions.

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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

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Published on: December 15, 2011

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Area of Science:

  • Dermatology
  • Virology
  • Immunocompromised Host Research

Background:

  • Atopic dermatitis (AD) is linked to an increased susceptibility to viral infections.
  • Disseminated viral infections can manifest within the eczematous skin lesions of AD patients.
  • Some of these viral complications represent dermatological medical emergencies.

Purpose of the Study:

  • To review the clinical significance of viral infections in atopic dermatitis.
  • To focus on eczema herpeticum as a primary viral complication of AD.
  • To highlight the pathogenesis and emergency nature of eczema herpeticum.

Main Methods:

  • Literature review of viral infections in atopic dermatitis.
  • Clinical case analysis of eczema herpeticum.
  • Pathogenesis review of herpes simplex virus in AD lesions.

Main Results:

  • Atopic dermatitis patients exhibit a higher incidence of viral infections (herpes simplex, molluscum contagiosum, verrucae vulgares).
  • Eczema herpeticum, a disseminated herpes simplex virus infection, is the most clinically relevant viral complication.
  • These infections, though rare, can be severe and require urgent dermatological attention.

Conclusions:

  • Eczema herpeticum is a critical viral complication in atopic dermatitis patients.
  • Understanding the pathogenesis is crucial for managing these emergent conditions.
  • Prompt recognition and treatment are essential for improving outcomes in AD patients with viral infections.