[Normogenesis of the cornea and its modification by cyclophosphamide in the animal experiment]

Animal experiments serving as models have hitherto been indispensable in order to explain pathogenetic processes in the development of malformations. The results presented here are contribution to studies on the normogenesis of the cornea in defined animal material (albino mice of Agnes Bluhm Jena-Halle stock). A single application of cyclophosphamide during embryogenesis caused inhibition malformations. Of these, different degrees of corneal hypoplasia and Peters' malformation are discussed in detail.