Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 23, 2026

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
11:34

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Published on: August 9, 2019

Aptamer Base: a collaborative knowledge base to describe aptamers and SELEX experiments.

Jose Cruz-Toledo1, Maureen McKeague, Xueru Zhang

  • 1Department of Biology, Carleton University, Ottawa, ON, Canada. jctoledo@connect.carleton.ca

Database : the Journal of Biological Databases and Curation
|March 22, 2012
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fluorescence Anisotropy Applied to Measure Aptamer-Protein Interactions.

Methods in molecular biology (Clifton, N.J.)·2026
Same author

Aptamers: Current Applications in Leukemia Diagnostics and Therapeutics.

Nucleic acid therapeutics·2026
Same author

Tunable gene expression in zebrafish using RiboSCALE.

bioRxiv : the preprint server for biology·2026
Same author

Enhancing Explainable AI Stability with Realistic Synthetic Data for Cardiovascular Risk Prediction.

Studies in health technology and informatics·2026
Same author

Translational opportunities in aptamer and nanobody lateral flow assays within the WHO REASSURED framework.

Sensors & diagnostics·2026
Same author

Publisher Correction: Unlocking chemical diversity in aptamers with DNA orthogonal barcodes.

Nature chemistry·2026

Aptamer Base is a new database organizing experimental data for aptamer selection and binding affinity. This structured resource aids researchers in the rapidly evolving field of aptamer research.

Area of Science:

  • Molecular biology
  • Bioinformatics
  • Biotechnology

Background:

  • Molecular recognition understanding has advanced due to molecular and information technology.
  • Aptamers, which are nucleic acid or amino acid polymers, are key in molecular recognition research due to their high-affinity binding.
  • Experimental data on aptamer selection and binding is often unstructured in publications.

Purpose of the Study:

  • To create a structured database for aptamer experimental data.
  • To centralize information on aptamer selection conditions and binding affinities.
  • To provide a community-driven resource for aptamer research.

Main Methods:

  • Development of the Aptamer Base database.
  • Structuring experimental data from peer-reviewed publications.

More Related Videos

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
12:31

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay

Published on: February 28, 2015

Mapping the Binding Site of an Aptamer on ATP Using MicroScale Thermophoresis
08:09

Mapping the Binding Site of an Aptamer on ATP Using MicroScale Thermophoresis

Published on: January 7, 2017

Related Experiment Videos

Last Updated: May 23, 2026

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
11:34

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Published on: August 9, 2019

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
12:31

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay

Published on: February 28, 2015

Mapping the Binding Site of an Aptamer on ATP Using MicroScale Thermophoresis
08:09

Mapping the Binding Site of an Aptamer on ATP Using MicroScale Thermophoresis

Published on: January 7, 2017

  • Implementing an open, collaborative, and decentralized curation system.

    • Main Results:

    • The Aptamer Base provides detailed, structured information on aptamer selection and binding affinity.
    • The database is designed for easy updating and curation by the research community.
    • It offers a centralized and accessible resource for aptamer-related experimental data.

    Conclusions:

    • The Aptamer Base addresses the need for structured data in aptamer research.
    • Its open and collaborative nature supports the dynamic field of aptamer development.
    • This database serves as a valuable resource for researchers studying aptamer selection and characterization.