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Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

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Tetrahymena Genome Database Wiki: a community-maintained model organism database.

Nicholas A Stover¹, Ravinder S Punia, Michael S Bowen

¹Department of Biology, Bradley University, Peoria, Illinois 61625, USA. nstover@bradley.edu

Database : the Journal of Biological Databases and Curation

|March 22, 2012

Summary

The Tetrahymena Genome Database (TGD) has been restored and updated as TGD Wiki. This community-driven resource empowers researchers to directly update gene information, ensuring a dynamic and accurate Tetrahymena bioinformatics platform.

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Area of Science:

Bioinformatics
Computational Biology
Genomics

Background:

The Tetrahymena Genome Database (TGD), a crucial resource, ceased updates in 2006 and went offline in 2008.
This discontinuation left a significant gap for the Tetrahymena research community.

Purpose of the Study:

To restore and update the Tetrahymena Genome Database.
To retool the database into an interactive platform (TGD Wiki) for community-driven updates.
To facilitate ongoing maintenance of Tetrahymena genome annotations.

Main Methods:

Restoration and updating of the existing TGD database.
Transitioning the TGD website to a wiki format (TGD Wiki).
Implementing web-based tools for direct community input on gene information (names, descriptions, Gene Ontology annotations).

Main Results:

The TGD has been successfully restored and updated.
The TGD Wiki is now operational, allowing direct community contributions.
A model for community-based genome annotation maintenance is demonstrated.

Conclusions:

Community-driven updates by primary data authors are a viable strategy for maintaining genome databases, especially for smaller research communities.
TGD Wiki enhances accessibility and participation for bench scientists in bioinformatics resource development.
The restored TGD Wiki serves as a vital, up-to-date resource for Tetrahymena research.