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Feverfew for migraine prophylaxis: a systematic review
Elisa Saranitzky1, C Michael White, Erica L Baker
1University of Connecticut, School of Pharmacy, Storrs, Connecticut, USA.
Journal of Dietary Supplements
|March 23, 2012
Summary
Feverfew may help prevent migraines in some individuals, according to a systematic review. Further research is needed to confirm long-term safety, especially for patients with coronary disease.
Area of Science:
- Phytomedicine
- Neurology
- Pharmacology
Background:
- Feverfew (Tanacetum parthenium) has been investigated for migraine treatment.
- Preliminary understanding exists regarding its pharmacologic mechanisms.
Purpose of the Study:
- To systematically review randomized controlled trials on feverfew for migraine.
- To present clinical findings and discuss potential implications.
Main Methods:
- Systematic review of randomized controlled trials (RCTs).
- Data collection and reporting analysis from individual studies.
Main Results:
- Individual study data did not permit result pooling.
- Evidence suggests feverfew benefits migraine prophylaxis in specific patient subsets.
- Cyclooxygenase-2 inhibiting effects raise potential long-term safety concerns.
Conclusions:
- Feverfew shows promise for migraine prophylaxis in certain populations.
- Longer-term studies are essential to address safety concerns, particularly for coronary disease patients.
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