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Conserved activation pathways in G-protein-coupled receptors

Xavier Deupi1, Jörg Standfuss, Gebhard Schertler

  • 1Laboratory of Biomolecular Research, Paul Scherrer Institut, Villigen PSI, Switzerland.

Biochemical Society Transactions
|March 23, 2012
PubMed
Summary

Structural insights into G-protein-coupled receptors (GPCRs) reveal conserved activation pathways. The structure of active rhodopsin provides a native-like model for understanding GPCR activation mechanisms.

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