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Updated: May 23, 2026

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia
07:46

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia

Published on: May 9, 2013

Carotid disease in acute ischemic stroke patients of northern Israel

G Telman1, E Sprecher, E Kouperberg

  • 1Department of Neurology, Rambam Medical Center, Haifa, Israel. g_telman@rambam.health.gov.il

Acta Neurologica Scandinavica
|March 23, 2012
PubMed

Insights

Demographic factors like age and male gender, along with vascular risks such as diabetes, hyperlipidemia, and smoking, are key predictors of carotid disease in stroke patients. Ethnicity did not significantly influence these findings.

Area of Science:

  • Neurology
  • Vascular Medicine
  • Epidemiology

Background:

  • Carotid artery disease is a significant risk factor for acute ischemic stroke.
  • Thrombosis and embolism originating from carotid plaques frequently lead to stroke.

Purpose of the Study:

  • To identify factors associated with carotid artery disease in patients experiencing acute ischemic stroke.
  • To investigate the role of demographic and vascular risk factors in carotid plaque development.

Main Methods:

  • A cohort of 1378 acute ischemic stroke patients was analyzed.
  • Cervical ultrasound was used to diagnose the presence of carotid plaques.
  • Logistic regression analysis was employed to determine independent predictors.

Main Results:

  • Age, male gender, diabetes, hyperlipidemia, and smoking were identified as independent predictors of carotid plaque.
  • Male gender showed a strong association with carotid stenosis (≥50%) and symptomatic plaques.
  • Age was the sole independent factor affecting the extent of carotid disease (bilateral vs. unilateral).
  • Initial ethnic differences in plaque prevalence (Jews vs. Arabs) were not significant after logistic regression.

Conclusions:

  • Demographic characteristics (age, gender) and vascular risk factors (diabetes, smoking, hyperlipidemia) are crucial determinants of carotid disease.
  • These factors are more influential than ethnic disparities in the studied population.
  • Understanding these determinants can aid in stroke prevention strategies.
Abstract

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