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Updated: May 23, 2026

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Published on: February 11, 2022
Right atrial surgery without caval snaring.
Reddy Dandolu1, Douglas Eaton, Aras Ali
1*Pennsylvania Hospital, University of Pennsylvania, Philadelphia, PA; and †Drexel University College of Medicine, Hahnemann Hospital, Philadelphia, PA.
Right atrial surgery is possible without caval snaring, preventing air entrainment from the inferior vena cava. Minimal air from the superior vena cava can be managed with clamping techniques.
Area of Science:
- Cardiovascular Surgery
- Medical Devices
Background:
- Tricuspid valve replacement may require right atrial access.
- Previous mitral valve surgery can complicate standard procedures.
- Incidental observation suggested right atrial opening without caval snaring is feasible.
Purpose of the Study:
- To test the hypothesis that the right atrium can be opened without caval snaring and without air entrainment.
- To evaluate air entrainment during right atrial surgery using percutaneous cannulation in an animal model.
Main Methods:
- Two patients underwent right atrial surgery with percutaneous cannulation without caval snaring.
- An animal model (2 pigs) was used to test the principle.
- Percutaneous cannulae were placed under epicardial echo guidance.
- A collapsible bag with air drainage system quantified air return from the superior vena (SVC) and inferior vena cava (IVC).
- Cannulae with and without proximal side holes were tested.
Main Results:
- No air entrainment occurred from the inferior vena cava (IVC) cannula in the animal model.
- Air was entrained from the superior vena cava (SVC) cannula at 60 mL/minute.
- Epicardial ultrasound showed complete collapse of both vena cavae.
- Partial clamping of the SVC cannula reduced air entrainment; a clamp at the SVC atrial junction eliminated it.
- No significant difference in air entrainment was observed between the two cannula types.
Conclusions:
- Inferior vena caval drainage via percutaneous cannula is safe without snaring, likely due to a competent Eustachian valve.
- The superior vena cava is susceptible to air entrainment during right atrial opening without snaring.
- Minimal SVC air entrainment can be managed with clamping techniques, avoiding the need for caval snaring.
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