Related Experiment Video
Updated: May 23, 2026

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
Outcomes after off-pump reoperative coronary artery bypass grafting
Cullen D Morris1, John D Puskas, Sorin V Pusca
1*Division of Cardiothoracic Surgery, Emory University School of Medicine, and †Department of Biostatistics, Rollins School of Public Health, Emory University, Atlanta, GA.
Insights
Off-pump (OPCAB) reoperative coronary artery bypass grafting (redo CABG) demonstrated reduced postoperative complications, transfusions, and shorter hospital stays compared to on-pump (ONCAB) procedures in selected patients.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery Outcomes
- Minimally Invasive Cardiac Procedures
Background:
- Reoperative coronary artery bypass grafting (redo CABG) presents unique challenges, including technical difficulty and risk of atheromatous embolism.
- Off-pump coronary artery bypass (OPCAB) techniques have been explored to mitigate these risks, but outcomes compared to traditional on-pump (ONCAB) methods require further investigation.
Purpose of the Study:
- To compare the clinical outcomes of off-pump (OPCAB) versus on-pump (ONCAB) techniques in patients undergoing reoperative coronary artery bypass grafting (redo CABG).
Main Methods:
- A retrospective chart review of 771 patients undergoing redo CABG between 1997 and 2004.
- Comparison of outcomes between OPCAB and ONCAB groups using propensity score matching to adjust for preoperative risk factors.
- Logistic regression analysis was employed to assess the association between surgical technique and various endpoints.
Main Results:
- OPCAB was associated with a significant reduction in postoperative complications, need for blood transfusion, incidence of atrial fibrillation, and length of hospital stay compared to ONCAB.
- Conversion rates were noted: 16.7% from OPCAB to ONCAB and 1.1% from ONCAB to OPCAB.
- OPCAB patients received fewer grafts, with comparable use of the left internal mammary artery conduit.
Conclusions:
- Off-pump coronary artery bypass (OPCAB) can be safely and effectively performed in selected patients undergoing reoperative coronary artery bypass grafting (redo CABG).
- The benefits of OPCAB, including reduced complications and shorter hospital stay, were maintained even when considering conversions to on-pump procedures.
Objective:
: Application of off-pump techniques to reoperative coronary artery bypass (redo CABG) has been limited by technical difficulty and potential for embolism of atheromatous debris from diseased grafts, resulting in myocardial infarction and rapid hemodynamic deterioration. We compared outcomes after off-pump (OPCAB) and on-pump (ONCAB) in redo CABG.
Methods:
: A retrospective chart review was performed for patients who underwent redo CABG at a single academic institution between January 1997 and December 2004. Outcomes were compared between groups based on intention to treat. Propensity scores were calculated for each patient using 23 preoperative risk factors. Logistic regression was applied for each end point as a function of group and propensity score.
Results:
: A total of 771 consecutive patients had redo CABG (639 ONCAB and 132 OPCAB); 22 patients (16.7%) were converted from OPCAB to ONCAB for hemodynamic in stability, severe adhesions, or graft injury; 7 patients (1.1%) were converted from ONCAB to OPCAB for severe aortic calcification. Propensity-matched comparison of outcomes after OPCAB versus ONCAB for redo CABG showed that OPCAB was associated with a reduction in postoperative complications, transfusion, atrial fibrillation, and length of stay. OPCAB patients received fewer grafts with similar use of left internal mammary artery conduit; conversion from OPCAB to ONCAB did not reduce the benefit of OPCAB.
Conclusions:
: OPCAB can be safely and effectively applied to reoperative CABG in selected cases.
Related Concept Videos
Peripheral Artery Disease V: Postoperative Nursing Management
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Coronary Artery Disease V: Interprofessional Care
