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Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
Coronary artery bypass grafts assessment at one year by noninvasive multislice computed tomography and invasive
Rajneesh Malhotra1, Manisha Mishra, Poonam Khurana
1From the Departments of *Cardiothoracic Surgery, †Cardiac Anesthesia, ‡Radioimaging, and §Cardiology, Escorts Heart Institute and Research Centre, New Delhi, India.
Insights
Multislice computed tomography (MSCT) accurately assesses coronary artery bypass graft patency one year after surgery, showing comparable results to invasive coronary angiography (ICA). This non-invasive method provides excellent resolution for evaluating graft health.
Area of Science:
- Cardiovascular Imaging
- Medical Diagnostics
- Surgical Outcomes
Background:
- Coronary artery bypass grafting (CABG) is a common treatment for multivessel coronary artery disease.
- Assessing long-term graft patency is crucial for patient outcomes.
- Non-invasive imaging modalities are sought to evaluate bypass graft status.
Purpose of the Study:
- To compare the diagnostic accuracy of multislice computed tomography angiography (MSCT) versus invasive coronary angiography (ICA) for evaluating coronary artery bypass graft patency.
- To assess graft patency at 1 year post-multivessel CABG surgery.
Main Methods:
- 114 patients who underwent CABG at least 1 year prior were evaluated.
- Both 16-slice CT angiography with cardiac gating and ICA were performed on all patients.
- Graft patency, occlusion, and stenosis were analyzed and compared between the two modalities.
Main Results:
- A total of 338 grafts were assessed; 6.25% showed occlusion or stenosis.
- MSCT demonstrated 100% specificity for stenosis detection.
- MSCT sensitivity for graft patency was 96.3%, with only 2 discrepancies compared to ICA.
Conclusions:
- MSCT angiography offers excellent resolution for postoperative assessment of coronary bypass grafts.
- Graft patency evaluation using MSCT is comparable in accuracy to ICA.
- MSCT is a reliable non-invasive tool for checking bypass graft status after surgery.
Objective:
: The aim of this study was to evaluate and compare the postoperative graft patency by multislice computed tomography (MSCT) and invasive coronary angiography (ICA) in patients with multivessel coronary artery bypass grafting at 1 year of surgery.
Methods:
: Patients (n = 114) who underwent isolated coronary artery bypass grafting at least 1 year (1.4 ± 0.4 years) previously were subjected to both 16-slice CT angiography with cardiac gating and ICA, and their results were evaluated and compared. All patients were receiving β-blockers; mean heart rate was 64 ± 6 beats/min.
Results:
: The mean age of the patients was 59.7 ± 8.5 years. There was a total of 338 grafts (113 internal mammary artery grafts, 8 radial artery grafts, and 217 saphenous venous grafts). On MSCT angiography, all the left internal mammary arteries were visualized with 3D reconstruction. All internal mammary arteries were found to be patent. Twenty-one grafts were occluded or stenosed (21/338, 6.25%). One occluded graft was on the anterior wall (1/20, 0.83%), 11 occluded grafts were on the lateral wall of the heart (11/128, 8.59%), and 9 occluded grafts were on the inferior wall of the heart (9/90, 10.0%); MSCT resulted in no false-positive diagnosis of stenosis (specificity, 100%). However, 2 grafts that were found to be patent on MSCT angiography were blocked on ICA (MSCT sensitivity, 96.3%).
Conclusions:
: Postoperative assessment of coronary bypass grafts is possible with an excellent resolution by MSCT angiography. Patency of bypass grafts can be checked by MSCT angiography, and the assessment is comparable with ICA.
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