Related Experiment Video
Updated: Aug 2, 2026
14:54
A Controlled Mouse Model for Neonatal Polymicrobial Sepsis
Published on: January 27, 2019
Postneonatal infectious disease mortality: the French situation
1School of Medicine, University of Nancy.
Pediatrics
|December 1, 1990
Summary
Infectious and parasitic diseases cause few, but preventable, postneonatal deaths in France. Further research is needed to clarify mortality statistics and improve infection control strategies.
Area of Science:
- Public Health
- Epidemiology
- Infectious Diseases
Background:
- Mortality from infectious and parasitic diseases constitutes a small but preventable fraction of postneonatal deaths in France.
- This mortality has remained stable over the last decade, highlighting the need for continued analysis and intervention.
Purpose of the Study:
- To analyze the impact of infectious and parasitic diseases on postneonatal mortality and morbidity in France.
- To discuss the definition of relevant disorders for accurate mortality comparisons.
- To review current policies and services for infection control and treatment in France.
Main Methods:
- Statistical analysis of mortality data related to infectious and parasitic diseases.
- Interpretation of trends and international rankings based on varying definitions.
- Description of existing public health policies and services for infection management.
Main Results:
- Infectious and parasitic diseases represent a limited portion of overall postneonatal deaths, which have been stable.
- The definition used significantly impacts mortality figures and international comparisons.
- Morbidity due to infections is substantial, leading to high incidence, hospitalization rates, and social costs.
Conclusions:
- Despite a limited contribution to overall mortality, infectious diseases pose a significant public health challenge due to preventability and morbidity.
- Clearer epidemiologic and statistical research is essential for accurate international comparisons of mortality.
- Existing policies require further development to address shortcomings in infection control and treatment.
Related Concept Videos
01:28Development of the Oral Microbiota
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
01:26Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
01:24Plague
Plague is a highly virulent zoonotic disease caused by Yersinia pestis, a Gram-negative, facultatively anaerobic coccobacillus. This pathogen primarily circulates among rodent populations and is transmitted to humans through the bite of infected fleas. Additional transmission routes include direct contact with infected animal tissue or inhalation of respiratory droplets from individuals with pneumonic plague. These multiple transmission pathways highlight the bacterium’s potential for rapid...
01:29Malaria
Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...
01:22Bacterial Meningitis I: Introduction
Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
01:26Bacterial Meningitis II: Pathophysiology
Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...