Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Immunological Memory01:23

Immunological Memory

Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature is...
Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

Overview
T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
Vaccines01:21

Vaccines

Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...
Special Features of Adaptive Immunity01:20

Special Features of Adaptive Immunity

The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pathological potential of autoantibodies in long COVID.

Nature reviews. Immunology·2026
Same author

Macrophages sample the living self.

Nature reviews. Immunology·2026
Same author

Neuron-eosinophil circuit explains stress-induced eczema flares.

Nature reviews. Immunology·2026
Same author

Early life allergen sensitivity starts in the skin.

Nature reviews. Immunology·2026
Same author

Spreading inflammation via the skin-joint axis.

Nature reviews. Immunology·2026
Same author

NK cells limit antibody breadth.

Nature reviews. Immunology·2025

Related Experiment Video

Updated: May 23, 2026

Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions
05:58

Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions

Published on: April 20, 2016

T cell memory: Skin-deep memory

Lucy Bird

    Nature Reviews. Immunology
    |March 23, 2012
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Lymphocyte Isolation from Human Skin for Phenotypic Analysis and Ex Vivo Cell Culture
    10:31

    Lymphocyte Isolation from Human Skin for Phenotypic Analysis and Ex Vivo Cell Culture

    Published on: April 8, 2016

    A Suction Blister Protocol to Study Human T-cell Recall Responses In Vivo
    11:17

    A Suction Blister Protocol to Study Human T-cell Recall Responses In Vivo

    Published on: August 11, 2018

    Related Experiment Videos

    Last Updated: May 23, 2026

    Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions
    05:58

    Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions

    Published on: April 20, 2016

    Lymphocyte Isolation from Human Skin for Phenotypic Analysis and Ex Vivo Cell Culture
    10:31

    Lymphocyte Isolation from Human Skin for Phenotypic Analysis and Ex Vivo Cell Culture

    Published on: April 8, 2016

    A Suction Blister Protocol to Study Human T-cell Recall Responses In Vivo
    11:17

    A Suction Blister Protocol to Study Human T-cell Recall Responses In Vivo

    Published on: August 11, 2018