Related Experiment Video
Updated: Oct 23, 2026
05:58
Tissue Triage and Freezing for Models of Skeletal Muscle Disease
Published on: July 15, 2014
Frostbite. Methods to minimize tissue loss
R L McCauley1, J P Heggers, M C Robson
1Department of Surgery, University of Texas Medical School, Galveston.
Postgraduate Medicine
|December 1, 1990
Abstract:
If frostbite is to be treated successfully, direct and indirect effects of injury must be understood. Rapid rewarming helps to preserve tissue by limiting the amount of direct cellular injury. Selective management of blisters helps protect the subdermal plexus, and application of Aloe vera cream (eg, Dermaide Aloe Cream) combats the local vasoconstrictive effects of thromboxane. Oral administration of ibuprofen decreases systemic levels of thromboxane.
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01:29Decreased Body Temperature
A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...