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Multicolor Flow Cytometry Analyses of Cellular Immune Response in Rhesus Macaques
07:11

Multicolor Flow Cytometry Analyses of Cellular Immune Response in Rhesus Macaques

Published on: April 22, 2010

OMIP-005: Quality and phenotype of antigen-responsive rhesus macaque T cells

Kathryn E Foulds1, Mitzi Donaldson, Mario Roederer

  • 1Nonhuman Primate Immunogenicity Core, Vaccine Research Center, NIAID, NIH, Bethesda, Maryland 20892, USA. FouldsK@niaid.nih.gov

Cytometry. Part a : the Journal of the International Society for Analytical Cytology
|March 23, 2012
PubMed
Abstract

No abstract available in PubMed .

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The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...

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