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Published on: June 29, 2013
Reference interval for fetal biometry in Italian population
Maurizio Giorlandino1, Francesco Padula, Pietro Cignini
1"Artemisia" Fetal-Maternal Medical Centre, Department of Prenatal Diagnosis, Rome, Italy.
Journal of Prenatal Medicine
|March 23, 2012
Summary
This study developed new fetal biometric charts and equations for the Italian population. These updated references improve the accuracy of fetal growth assessments in clinical practice.
Area of Science:
- Obstetrics and Gynecology
- Fetal Medicine
- Biometry
Background:
- Accurate fetal biometry is crucial for monitoring pregnancy progression and identifying potential growth abnormalities.
- Existing fetal growth charts may not accurately reflect diverse populations, necessitating localized reference data.
Purpose of the Study:
- To validate and establish new reference charts and equations for fetal biometry.
- To create population-specific data for an unselected Italian cohort.
Main Methods:
- A cross-sectional study of 4896 singleton pregnancies was conducted.
- Fetal biometric measurements were recorded between 14 and 40 weeks of gestation.
- Regression models were used to estimate percentiles and Z-scores for fetal parameters.
Main Results:
- New fetal reference charts and equations were developed for the Italian population.
- The study utilized a robust statistical procedure for data analysis.
- The generated data provides updated centiles for fetal biometric measurements.
Conclusions:
- This is the first Italian study of its kind with a large sample size.
- The new fetal biometric charts are valuable tools for obstetrical clinical practice in Italy.
- These updated references enhance the assessment of fetal growth in the target population.

