Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: May 23, 2026

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Published on: December 27, 2024

Metastatic spinal tumor.

Chong-Suh Lee¹, Chul-Hee Jung

¹Department of Orthopaedic Surgery, Spine Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Asian Spine Journal

|March 23, 2012

Summary

This summary is machine-generated.

Related Concept Videos

Metastasis

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Risk Factors of Revision Surgery After Acute Proximal Junctional Fracture Following Adult Spinal Deformity Surgery.

Neurosurgery·2026

Same author

Machine Learning-Based Identification of Distinct Risk Factors for Moderate vs Severe Proximal Junctional Kyphosis After Adult Spinal Deformity Surgery.

The spine journal : official journal of the North American Spine Society·2026

Same author

Comparative Analysis of Three Lordosis Correction Parameters for Predicting Proximal Junctional Kyphosis in Adult Spinal Deformity Surgery.

Spine·2026

Same author

Effect of high BMI and overcorrected lordosis distribution index on the risk of proximal junctional kyphosis after age-adjusted sagittal correction in adult spinal deformity.

Journal of neurosurgery. Spine·2026

Same author

Hierarchical deep learning pipeline for robust cervical parameter measurement in radiographs with C7 obscuration.

NPJ digital medicine·2026

Same author

Minimally invasive techniques and enabling technologies for adult spinal deformity: state of the art and future directions.

Asian spine journal·2026

Same journal

Preoperative coronal magnetic resonance imaging: a critical evaluation of the Kambin's triangle for the transforaminal lumbar interbody fusion procedure.

Asian spine journal·2026

Same journal

Comparison between endoscopic lumbar discectomy with and without annulus fibrosus suturing: a systematic review and meta-analysis.

Asian spine journal·2026

Same journal

Magnetic resonance imaging-derived vertebral bone quality correlates with computed tomography-derived bone density and paraspinal muscle degeneration: a systematic review and meta-analysis.

Asian spine journal·2026

Same journal

Differential association of psoas and paraspinal muscle volumes with appendicular lean mass index: AI-derived lumbar computed tomography three-dimensional volumetric indices in older Korean Women: an observational study.

Asian spine journal·2026

Same journal

The top-down driver: a comprehensive review of cervical alignment as the final frontier for global spinal sagittal balance and its practical application in deformity correction.

Asian spine journal·2026

Same journal

Effects of conservative exercise-based interventions on spinal curvature, respiratory function, and quality of life in patients with idiopathic scoliosis: a systematic review and meta-analysis.

Asian spine journal·2026

See all related articles

Metastatic spinal tumors are increasing due to longer cancer survival. Effective treatment focuses on quality of life, including pain relief and spinal stability, rather than survival extension.

Area of Science:

Oncology
Neurosurgery
Radiology

Background:

Increasing survival rates for cancer patients have led to a rise in metastatic spinal tumors.
Advances in diagnostic radiology, chemotherapy, and surgical techniques have improved metastatic spine tumor treatment outcomes.
Surgical indications for metastatic spine tumors are expanding due to improved treatment efficacy.

Purpose of the Study:

To review the current understanding of metastatic spinal tumors.
To emphasize the importance of a multidisciplinary approach in managing these complex cases.
To highlight the shift in treatment goals towards improving patient quality of life.

Main Methods:

Review of current literature on metastatic spinal tumors.
Analysis of treatment advancements in radiology, chemotherapy, and surgical interventions.

Keywords:

Metastasis Neoplasm Spine

Related Experiment Videos

Last Updated: May 23, 2026

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Published on: December 27, 2024

Discussion of diagnostic and treatment principles.

Main Results:

Improved outcomes for metastatic spine tumors due to advancements in diagnostics, chemotherapy, and surgical techniques.
Increased surgical indications for metastatic spinal tumors.
Focus on pain relief, neurological preservation, and spinal stability for enhanced quality of life.

Conclusions:

Effective management of metastatic spinal tumors requires a thorough understanding of etiology, diagnosis, and treatment principles.
Treatment goals prioritize quality of life through pain management, functional preservation, and spinal stabilization.
Multidisciplinary collaboration is crucial for optimizing treatment plans and patient outcomes.