Aggressive form of cherubism
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Updated: May 23, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
Gv Reddy1, G Siva Prasad Reddy, Nvs Sekhar Reddy
1Department of Oral and Maxillofacial Surgery, Panineeya Institute of Dental Sciences, Hyderabad, Andhra Pradesh, India.
Abstract:
Cherubism is a rare non-neoplastic hereditary disease related to genetic mutations characterized by symmetrically swollen cheeks, particularly over the angles of the mandible, and an upward turning of the eyes. The affected mandible and maxilla begin to swell in early childhood, and gradually increase until the age of puberty. Apparently, surgical intervention is unnecessary unless significant functional, esthetic, or emotional disturbances develop. In the present paper, we report a case of cherubism, with classic features that was classified as grade 3, managed with surgery and followed up for 2-years after treatment.
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