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Related Experiment Video

Updated: May 23, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Aggressive form of cherubism.

Gv Reddy¹, G Siva Prasad Reddy, Nvs Sekhar Reddy

¹Department of Oral and Maxillofacial Surgery, Panineeya Institute of Dental Sciences, Hyderabad, Andhra Pradesh, India.

Journal of Clinical Imaging Science

|March 23, 2012

Summary

Cherubism, a rare genetic disorder causing facial swelling, typically doesn't require surgery. This case study details successful surgical management for a severe cherubism presentation.

Keywords:

Cherubism hereditary multilocular cystic lesion non-neoplastic lesion

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Area of Science:

Genetics
Oral and Maxillofacial Surgery
Pediatric Dentistry

Background:

Cherubism is a rare, autosomal dominant genetic disorder.
Characterized by symmetrical enlargement of the mandible and maxilla, leading to characteristic facial features.
Typically presents in early childhood and progresses until puberty.

Observation:

A case of cherubism with classic features, classified as grade 3, is presented.
The patient exhibited significant functional and esthetic disturbances.
Surgical intervention was deemed necessary due to the severity of the condition.

Findings:

Surgical management of the grade 3 cherubism case was performed.
The patient was followed up for two years post-treatment.
The surgical intervention resulted in positive outcomes, addressing the functional and esthetic concerns.

Implications:

This case highlights the potential role of surgical intervention in managing severe cherubism.
Early diagnosis and appropriate management are crucial for improving patient quality of life.
Further research into genetic factors and long-term outcomes of surgical treatments is warranted.