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Related Experiment Videos

Hepatic infarction in preeclampsia.

A J Kronthal1, E K Fishman, J E Kuhlman

  • 1Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins Hospital, Baltimore, MD 21205.

Radiology
|December 1, 1990
PubMed
Summary

Hepatic infarction, a rare complication of pregnancy toxemia, is associated with HELLP syndrome. Imaging findings on CT, MRI, and ultrasound help distinguish these liver abnormalities.

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Area of Science:

  • Obstetrics and Gynecology
  • Radiology
  • Hepatology

Background:

  • Toxemia of pregnancy, also known as pre-eclampsia, can lead to severe maternal complications.
  • HELLP syndrome (hemolytic anemia, elevated liver enzymes, and low platelets) is a serious condition often associated with pre-eclampsia.
  • Hepatic infarction, or liver tissue death, is a rare but critical manifestation.

Purpose of the Study:

  • To describe two cases of hepatic infarction in pregnant patients with HELLP syndrome.
  • To detail the characteristic imaging findings of hepatic infarction in this specific patient population.

Main Methods:

  • Review of two cases of hepatic infarction in patients with toxemia of pregnancy and HELLP syndrome.
  • Analysis of computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound findings.
  • Correlation of imaging features with clinical and laboratory data.

Main Results:

  • Both patients presented with laboratory findings consistent with HELLP syndrome.
  • CT scans revealed nonenhancing, low-attenuation areas in the liver, varying in shape and size.
  • MRI demonstrated corresponding areas of low signal intensity on T1-weighted and high signal intensity on T2-weighted images.
  • Ultrasound showed well-defined, peripheral hypoechoic lesions.

Conclusions:

  • Hepatic infarction can occur in the context of HELLP syndrome during pregnancy.
  • Characteristic imaging features, including low attenuation and lack of enhancement on CT, are key for diagnosis.
  • Multimodality imaging plays a crucial role in identifying and characterizing hepatic infarction in pregnant patients.

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