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Intussusception among Japanese children: an epidemiologic study using an administrative database
Masato Takeuchi1, Toshio Osamura, Hideo Yasunaga
1Department of Pediatrics, The University of Tokyo Hospital, Tokyo, Japan. masatotakeuchi@gmail.com
Childhood intussusception incidence in Japan is higher than previously reported, with an estimated 180-190 cases per 100,000 infants annually. Most cases were successfully treated with enema, with surgery required in the remainder.
Area of Science:
- Pediatrics
- Epidemiology
- Gastroenterology
Background:
- Intussusception epidemiology varies globally.
- Childhood intussusception incidence data in Japan is limited.
- This study addresses the need for updated epidemiological data in Japan.
Purpose of the Study:
- To describe the epidemiology of childhood intussusception in Japan.
- To estimate the incidence of intussusception in Japanese children.
- To analyze demographics, management, and outcomes of intussusception cases.
Main Methods:
- Utilized a nationwide inpatient database from July to December 2007-2008.
- Included children aged ≤18 years with intussusception diagnosis (ICD-10: K-561).
- Applied Brighton Collaboration diagnostic certainty criteria (Level 1) and analyzed case data.
Main Results:
- Identified 2,427 intussusception cases.
- Estimated annual incidence of 180-190 cases per 100,000 infants.
- Median age 17 months, 66% male; 93% enema success rate; 3.1% secondary cases; 2 fatal cases.
Conclusions:
- Largest Asian survey of childhood intussusception using standardized criteria.
- Provides baseline risk estimate for intussusception in Japan.
- Incidence in Japan is higher than reported in other countries.
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