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04:38
A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
Published on: May 22, 2019
Depression improvement is related to social role functioning after stroke
Arlene A Schmid1, Teresa Damush, Wanzhu Tu
1Roudebush Veterans Administration Medical Center, Health Services Research and Development Center on Implementing Evidence-Based Practice, Indianapolis, IN 46202, USA. arlene.schmid@va.gov
Archives of Physical Medicine and Rehabilitation
|March 24, 2012
Summary
Improving depression in stroke survivors is key to enhancing their social role functioning (SRF). Early screening and treatment of post-stroke depression are vital for rehabilitation.
Area of Science:
- Neurology
- Psychiatry
- Rehabilitation Medicine
Background:
- Stroke frequently leads to social role functioning (SRF) deficits.
- Post-stroke depression is a common complication impacting recovery and quality of life.
Purpose of the Study:
- To identify factors associated with SRF 4 months post-stroke.
- To determine if depression improvement predicts SRF in stroke survivors.
Main Methods:
- Secondary analysis of a cohort study (N=371) of stroke survivors.
- Multiple linear regression used to assess associations with 12-week SRF.
- Depression measured by PHQ-9; SRF by Stroke-Specific Quality of Life Scale.
Main Results:
- Baseline depression and comorbidities were independently associated with 12-week SRF.
- Depression improvement independently predicted SRF in the depressed subgroup.
Conclusions:
- For stroke survivors with depression, improved mood was linked to better SRF.
- Rehabilitation providers should prioritize screening and treating post-stroke depression to improve social functioning.
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