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Updated: May 23, 2026
06:32
Evaluation of Biomarkers in Glioma by Immunohistochemistry on Paraffin-Embedded 3D Glioma Neurosphere Cultures
Published on: January 9, 2019
Pathology: commonly monitored glioblastoma markers: EFGR, EGFRvIII, PTEN, and MGMT
Joaquin Q Camara-Quintana1, Ryan T Nitta, Gordon Li
1Department of Neurosurgery, Stanford University, 1201 Welch Road, MSLS p309, Stanford, CA 94305, USA.
Neurosurgery Clinics of North America
|March 24, 2012
Abstract:
The purpose of this article is to update the neurosurgical field on current molecular markers important to glioblastoma biology, treatment, and prognosis. The highlighted biologic markers in this article include epidermal growth factor receptor (EGFR), EGFR variant III (EGFRvIII), phosphatase and tensin homolog deleted on chromosome 10 (PTEN), and O6-methylguanine-DNA methyltransferase (MGMT).
