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6-Substituted quinoline-based ratiometric two-photon fluorescent probes for biological Zn2+ detection
Xiangming Meng1, Shuxin Wang, Yiming Li
1Department of Chemistry, Anhui University, Hefei 230039, P.R. China. mengxm@ahu.edu.cn
Abstract:
New ratiometric two-photon fluorescent probes are developed from 6-substituted quinolines for biological Zn(2+) detection. They show large red shifts and good ratiometric responses upon Zn(2+) binding. They also exhibit high ion selectivities and large two-photon absorption cross sections at nearly 720 nm. Because the new probes are cell-permeable, they can be used to detect intracellular zinc flux under two-photon excitation.
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