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Venous Thrombosis III: Interprofessional Care

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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...

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Drug Dosing: Geriatric Patients

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...

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Updated: May 23, 2026

Prehospital Thrombolysis: A Manual from Berlin

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

[Thrombosis prophylaxis in geriatric patients].

R E Roller¹, P Feichtinger

¹Fachbereich Geriatrie und kompetenzbasierte Curriculumsentwicklung, Medizinische Universität Graz, Auenbruggerplatz 15, 8036, Graz, Österreich. Regina.Roller-Wirnsberger@medunigraz.at

Zeitschrift Fur Gerontologie Und Geriatrie

|March 24, 2012

Summary

Older, multimorbid patients face a high risk of thromboembolic disease. Despite guidelines, many, especially the elderly, don't receive necessary pharmacological prophylaxis.

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Last Updated: May 23, 2026

Prehospital Thrombolysis: A Manual from Berlin

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

Area of Science:

Geriatrics
Internal Medicine
Pharmacology

Context:

Older, multimorbid patients have an elevated risk of thromboembolic disease.
Deep vein thrombosis incidence rises with age and in hospital settings.
Current guidelines recommend pharmacological prophylaxis, yet adherence is suboptimal, particularly in the very old and multimorbid.

Purpose:

To summarize the pathophysiological and clinical factors contributing to thromboembolism risk in geriatric patients.
To review available pharmacological agents for thromboembolic prophylaxis.
To highlight specific considerations for using these drugs in the elderly population.

Summary:

Geriatric patients, especially those with multiple comorbidities, are highly susceptible to thromboembolic events.
Pharmacological prophylaxis is the standard of care but is underutilized in this vulnerable group.
This review details the rationale and current therapeutic options for preventing thromboembolism in the elderly.

Impact:

Addresses a critical gap in the care of high-risk geriatric patients.
Provides essential information for clinicians managing thromboembolism risk in older adults.
Aims to improve guideline adherence and patient outcomes through better understanding and application of prophylaxis.