Related Experiment Video
Updated: May 23, 2026

10:35
Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis
Published on: October 17, 2016
A beam-splitter-type 3-D endoscope for front view and front-diagonal view images
Hiroki Kamiuchi1, Ken Masamune, Kenta Kuwana
1Graduate School of Information Science and Technology, The University of Tokyo, Tokyo, Japan. khiroki@atre.t.u-tokyo.ac.jp
Summary
This new 3-D endoscope offers front and front-diagonal views, reducing surgical risks. Rotating the inner sleeve allows easy switching, enhancing safety for delicate tissue manipulation during endoscopic procedures.
Area of Science:
- Medical Engineering
- Surgical Technology
- Optical Imaging
Background:
- Endoscopic surgery requires surgeons to estimate instrument depth from 2-D images, risking tissue damage.
- Current 3-D endoscopes may have limitations in field-of-view and depth perception.
Purpose of the Study:
- To develop a novel Ø7 mm 3-D endoscope capable of switching between front and front-diagonal views.
- To reduce the risk of damaging delicate body tissues during endoscopic procedures.
Main Methods:
- The 3-D endoscope incorporates a beam splitter and polarization plates within rotating sleeves.
- Key optical parameters including signal-to-noise ratio (SNR), sharpness, chromatic aberration (CA), and viewing angle were measured.
- Feasibility was evaluated through in vivo experiments.
Main Results:
- The developed 3-D endoscope achieved a viewing angle of approximately 50° for both front and front-diagonal views.
- Compared to conventional 3-D endoscopes, SNR decreased by 20% and sharpness by 7%, with no significant difference in CA.
- Clear 3-D images from both views were successfully obtained in vivo by rotating the inner sleeve.
Conclusions:
- The developed 3-D endoscope effectively provides switchable front and front-diagonal views.
- This capability significantly decreases the risk of iatrogenic damage to fragile body tissues during surgery.
Related Concept Videos
Three-Dimensional Microscopy in Microbiology
Three-dimensional imaging techniques are essential in cell biology, allowing researchers to visualize intricate cellular structures with high resolution. Two prominent methods, Differential Interference Contrast Microscopy (DIC) and Confocal Scanning Laser Microscopy (CSLM), provide distinct advantages for imaging live and thick specimens, respectively.Differential Interference Contrast MicroscopyDIC microscopy enhances contrast in transparent, unstained samples by converting phase...
Confocal Fluorescence Microscopy
Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
