Related Experiment Video
Updated: May 23, 2026
Intramyocardial Cell Delivery: Observations in Murine Hearts
Published on: January 24, 2014
A new heart: somatic stem cells and myocardial regeneration
Philip S Mullenix1, Steven J Huddleston, Alexander Stojadinovic
1Department of Surgery, Veterans Affairs Medical Center, Washington, District of Columbia, Washington, District of Columbia 20307, USA. philip.mullenix@va.gov
Abstract:
End-stage heart failure is a global scourge. Current therapies merely delay its inexorable progression. Heart transplantation is resource-intensive and limited by organ availability. Bone marrow-derived and cardiac-specific stem cells have demonstrated potential for cardiac regeneration and repair, but the magnitude and durability of these promising findings are inconsistent. The purpose of this review is to (1) describe cells currently being investigated, (2) outline the status of current trials, and (3) discuss key objectives of future research.
