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[Lymphographic examinations in the pediatric age: review of 413 cases]
Insights
Pediatric lymphography is a safe and accurate diagnostic tool for childhood cancers. This study demonstrates its effectiveness in treatment planning and detecting tumor recurrence in children.
Area of Science:
- Pediatric Oncology
- Diagnostic Imaging
Background:
- Lymphography is an established imaging technique for evaluating lymphatic system involvement in various diseases.
- Its application and safety in pediatric populations require specific investigation.
Purpose of the Study:
- To assess the feasibility, safety, and diagnostic accuracy of lymphography in children under 15 years of age.
- To evaluate the utility of pediatric lymphography in cancer staging, treatment planning, and follow-up.
Main Methods:
- A retrospective analysis of 413 children under 15 who underwent lymphography between January 1969 and June 1978.
- Assessment of successful lymphatic cannulation rates, complication incidence, and lymphographic-histologic correlation in biopsied cases.
Main Results:
- Successful lymphatic cannulation was achieved in 97.7% of attempted sites.
- No major or permanent complications were reported.
- Lymphographic-histologic correlation demonstrated high accuracy (94.5%) in cases with biopsy.
Conclusions:
- Pediatric lymphography is technically feasible and safe, comparable to adult procedures.
- The diagnostic accuracy of lymphography in childhood is acceptable.
- Lymphography is a valuable tool for treatment planning, assessing therapeutic response, and detecting recurrent tumors in pediatric oncology.
Abstract:
From January 1969-June 1978, 413 children less than 15 years of age underwent lymphography at the National Cancer Institute, Milan. Successful lymphatic cannulation was accomplished in 97.7% (769/787) of the sites where it was attempted. No major or permanent complications were encountered. In those children undergoing biopsy of opacified lymph nodes, lymphographic-histologic correlation was 94.5% (104/110). This study has shown that lymphography in childhood can be as readily performed as in the adult and that its diagnostic accuracy is acceptable. As in adults, it is useful in treatment planning, evaluating results of therapy, and detecting recurrent tumor.