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Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri
Published on: September 12, 2025
Total laparoscopic hysterectomy for large uterus.
Rakesh Sinha1, Meenakshi Sundaram, Smita Lakhotia
1Beams Hospital, Mumbai - 400 052, India.
Journal of Gynecological Endoscopy and Surgery
|March 24, 2012
Summary
Total laparoscopic hysterectomy (TLH) is feasible for very large uteri, even those over 500 grams. Experienced surgeons can efficiently perform TLH on large myomatous uteri, irrespective of fibroid characteristics.
Area of Science:
- Gynecological Surgery
- Minimally Invasive Procedures
- Reproductive Health
Background:
- Uterine fibroids are common, often leading to symptomatic conditions requiring hysterectomy.
- Large uteri present surgical challenges for traditional and minimally invasive hysterectomy.
- Total laparoscopic hysterectomy (TLH) offers potential benefits but its feasibility for very large uteri is debated.
Purpose of the Study:
- To assess the feasibility of performing total laparoscopic hysterectomy (TLH) for uteri weighing over 500 grams.
- To evaluate the efficacy of TLH in cases of large myomatous uteri, irrespective of fibroid size, number, or location.
- To determine if experienced laparoscopic surgeons can efficiently manage large uteri via TLH.
Main Methods:
- Retrospective review of 173 women undergoing TLH at a high-volume gynecological laparoscopy center.
- No exclusion criteria based on uterine size, myoma characteristics, or location.
- Surgical modifications included pre-ligation of uterine arteries, myomectomy followed by hysterectomy, and direct morcellation.
Main Results:
- The average uterine specimen weight was 700 grams (range: 500-2240 grams).
- Average surgical duration was 107 minutes (range: 40-300 minutes) with an average blood loss of 228 ml (range: 10-3200 ml).
- 72% of patients had prior normal vaginal delivery, and 28% had prior cesarean sections.
Conclusions:
- Total laparoscopic hysterectomy is a technically feasible procedure for large uteri.
- Experienced surgeons can successfully perform TLH on large myomatous uteri regardless of fibroid complexity.
- TLH is a viable option for managing symptomatic large fibroids, offering a minimally invasive approach.

