Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Exploring the Connection between <i>Porphyromonas gingivalis</i> and Neurodegenerative Diseases: A Pilot Quantitative Study on the Bacterium Abundance in Oral Cavity and the Amount of Antibodies in Serum.

Biomolecules·2021

Same author

Therapeutic Potential of Antibody-Drug Conjugate-Based Therapy in Head and Neck Cancer: A Systematic Review.

Cancers·2021

Same author

Cortical Thickness, Bone Density, and the Insertion Torque/Depth Integral: A Study Using Polyurethane Foam Blocks.

The International journal of oral & maxillofacial implants·2021

Same author

Case Report: Histological and Histomorphometrical Results of a 3-D Printed Biphasic Calcium Phosphate Ceramic 7 Years After Insertion in a Human Maxillary Alveolar Ridge.

Frontiers in bioengineering and biotechnology·2021

Same author

Biphasic Calcium Phosphate Biomaterials: Stem Cell-Derived Osteoinduction or In Vivo Osteoconduction? Novel Insights in Maxillary Sinus Augmentation by Advanced Imaging.

Materials (Basel, Switzerland)·2021

Same author

Cold atmospheric plasma coupled with air abrasion in liquid medium for the treatment of peri-implantitis model grown with a complex human biofilm: an in vitro study.

Clinical oral investigations·2021

Search research articles

Related Experiment Video

Updated: May 23, 2026

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials

Published on: August 13, 2019

Bone regeneration with algae-derived hydroxyapatite: a pilot histologic and histomorphometric study in rabbit tibia

Antonio Scarano¹, Vittoria Perrotti, Marco Degidi

¹Dental School, University of Chieti-Pescara, Chieti, Italy.

The International Journal of Oral & Maxillofacial Implants

|March 24, 2012

Summary

Algipore, a biologic hydroxyapatite from algae, demonstrated high osteoconductivity and resorbability in rabbit tibia defects. New bone formation was observed around and within the Algipore particles.

More Related Videos

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

Published on: May 21, 2013

Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model

Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model

Published on: May 21, 2013

Related Experiment Videos

Last Updated: May 23, 2026

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials

Published on: August 13, 2019

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

Published on: May 21, 2013

Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model

Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model

Published on: May 21, 2013

Area of Science:

Biomaterials Science
Orthopedic Research
Regenerative Medicine

Background:

Algipore is a biologic hydroxyapatite derived from marine algae.
Biomaterials are crucial for bone defect repair and regeneration.

Purpose of the Study:

To evaluate the histological and histomorphometric properties of Algipore after implantation in rabbit tibia defects.
To assess the osteoconductivity and resorbability of Algipore.

Main Methods:

Surgical creation of 7-mm tibia defects in six New Zealand rabbits.
Implantation of Algipore into test defects, with control defects left empty.
Histological and histomorphometric analysis of retrieved specimens after 4 weeks.

Main Results:

Significant new bone formation was observed around and within Algipore particles in test defects.
The percentage of contact between newly formed bone and Algipore particles was 71.2%.
Newly formed bone occupied 31.1% of test sites, with residual Algipore at 33.4% and marrow spaces at 34.7%.

Conclusions:

Algipore exhibits high osteoconductivity, promoting bone regeneration.
The biomaterial shows evidence of resorbability within the defect site.
Algipore is a promising material for bone defect repair.