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Related Concept Videos

Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Adult Stem Cells01:33

Adult Stem Cells

Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously renew...
Embryonic Stem Cells00:57

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Embryonic Stem Cells00:58

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...
Induced Pluripotent Stem Cells01:06

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic cells are...

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Updated: May 23, 2026

Tracheotomy: A Method for Transplantation of Stem Cells to the Lung
03:45

Tracheotomy: A Method for Transplantation of Stem Cells to the Lung

Published on: February 25, 2007

Human lung stem cells: has the future arrived?

Jennifer M Hanna, Mark W Onaitis

    Seminars in Thoracic and Cardiovascular Surgery
    |March 27, 2012
    PubMed
    Summary
    This summary is machine-generated.

    Researchers identified c-kit-positive human lung stem cells capable of self-renewal and differentiation. These findings offer potential therapeutic applications, though further investigation is warranted.

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    Procedure for Lung Engineering
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    Area of Science:

    • Pulmonology
    • Stem Cell Biology
    • Regenerative Medicine

    Background:

    • Recent publication details c-kit-positive human lung stem cells.
    • These cells exhibit self-renewal and multi-lineage differentiation capabilities.

    Discussion:

    • The study raises important questions regarding the precise mechanisms and potential applications.
    • Critical review of the findings and emerging issues is presented.

    Key Insights:

    • Identification of a novel human lung stem cell population.
    • Demonstration of self-renewal and differentiation potential in vitro.
    • Potential implications for lung regeneration and disease treatment.

    Outlook:

    • Further research is needed to validate these findings and explore therapeutic avenues.
    • Addressing the unanswered questions is crucial for clinical translation.
    • Future studies may focus on targeted therapies using these stem cells.