Related Experiment Video
Updated: May 23, 2026

04:47
Isolation of Umbilical Cord-Derived Mesenchymal Stem Cells with High Yields and Low Damage
Published on: July 5, 2024
Patterns of breaks in umbilical cords by different mechanisms
Samantha R Evans1, Darinka Mileusnic-Polchan
1Department of Pathology, The University of Tennessee Medical Center, Knoxville, TN 37920, USA. sevans@utmck.edu
Journal of Forensic Sciences
|March 27, 2012
Summary
Forensic analysis can differentiate how umbilical cords were cut. Blunt force and sharp force injuries show distinct patterns, aiding investigations into perinatal deaths.
Area of Science:
- Forensic pathology
- Obstetrics
- Pediatric pathology
Background:
- Discrepancies between autopsy findings and witness accounts are common in perinatal death investigations.
- Determining the method of umbilical cord severance is crucial for investigative accuracy.
- Objective data on umbilical cord severance mechanisms is currently limited.
Purpose of the Study:
- To investigate and differentiate the morphological characteristics of umbilical cords severed by various mechanisms.
- To establish objective criteria for identifying the tool or force used to sever an umbilical cord.
Main Methods:
- Examined 99 placentas with umbilical cords.
- Randomly severed cords using knives, scissors, traction, or crush.
- Documented gross and microscopic features of the severed ends.
- Photographed each break for detailed analysis.
Main Results:
- Gross examination revealed distinct morphological differences between blunt and sharp force cord severances.
- Microscopic examination of tissue sections provided further differentiating features.
- Specific patterns of injury were identified for different sharp force mechanisms.
Conclusions:
- Umbilical cord morphology provides reliable indicators of the severance mechanism.
- Objective differentiation between blunt and sharp force trauma to the umbilical cord is achievable.
- This research offers valuable data for forensic investigations involving perinatal deaths.
More Related Videos
Related Concept Videos
Fetal Circulation
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Embryonic Connective Tissues
During early development, the embryo forms two types of connective tissues— the mesenchyme and mucoid connective tissue.
The mesenchyme is the first connective tissue that emerges in the developing embryo. It consists of loosely arranged multipotent mesenchymal cells and reticular fibers in the extracellular matrix. This loose arrangement allows easy migration of cells, which is essential for germ layer positioning, patterning, and organ morphogenesis during embryonic development. Mesenchyme is...
The mesenchyme is the first connective tissue that emerges in the developing embryo. It consists of loosely arranged multipotent mesenchymal cells and reticular fibers in the extracellular matrix. This loose arrangement allows easy migration of cells, which is essential for germ layer positioning, patterning, and organ morphogenesis during embryonic development. Mesenchyme is...
Development of Blood Vessels
The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
Spinal Cord Injury ll: Pathophysiology
Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...

