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Related Concept Videos

Antiasthma Drugs: β2-Adrenoceptor Agonists01:25

Antiasthma Drugs: β2-Adrenoceptor Agonists

Bronchodilators are critical in managing asthma, a chronic respiratory condition characterized by airway constriction due to inflammation and hyper-reactivity. Specifically, bronchodilators ease this constriction by relaxing the bronchial muscles, facilitating easier breathing.
One class of bronchodilators includes β2-adrenoceptor agonists. These agents target the β2-adrenoceptors located on bronchial smooth muscle cells. By stimulating these receptors, β2-agonists induce relaxation in these...
Inhaled Medications01:23

Inhaled Medications

Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Adrenergic Agonists: Therapeutic Classification01:18

Adrenergic Agonists: Therapeutic Classification

Adrenergic agonists can be classified based on their therapeutic uses and mechanisms of action. They serve various purposes in clinical applications.
Vasopressor or pressor agents: They increase blood pressure and function as cardiac stimulants. Examples include endogenous catecholamines (norepinephrine and dopamine) and synthetic agents (phenylephrine).
Bronchodilators: β2-agonists can relax bronchial muscles and widen airways. They are commonly used for treating obstructive pulmonary...
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:

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Updated: May 23, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

New bronchodilators.

Garbo Mak1, Nicola A Hanania

  • 1Section of Pulmonary, Critical Care and Sleep Medicine, Baylor College of Medicine, Houston, TX, United States.

Current Opinion in Pharmacology
|March 27, 2012
PubMed
Summary
This summary is machine-generated.

Novel bronchodilators for chronic obstructive pulmonary disease (COPD) focus on improved dosing and safety, alongside exploring new targets like EP4 agonists and selective PDE inhibitors for better treatment outcomes.

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Methodology for Sputum Induction and Laboratory Processing
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Methodology for Sputum Induction and Laboratory Processing

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Related Experiment Videos

Last Updated: May 23, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Published on: November 4, 2010

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
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Methodology for Sputum Induction and Laboratory Processing

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Area of Science:

  • Pharmacology and Respiratory Medicine
  • Drug Discovery and Development

Background:

  • Bronchodilators are essential for managing airway diseases, particularly chronic obstructive pulmonary disease (COPD).
  • Current COPD treatment goals include improving lung function, reducing symptoms, preventing exacerbations, and enhancing patient quality of life.

Purpose of the Study:

  • To review emerging bronchodilators for COPD treatment.
  • To highlight novel pharmacologic targets and combination therapies in bronchodilator development.

Main Methods:

  • Review of preclinical data for novel bronchodilators.
  • Analysis of available clinical trial information for emerging therapies.

Main Results:

  • Development programs are enhancing existing bronchodilator targets for once-daily dosing and improved safety.
  • Research is actively exploring novel targets, including EP4 receptor agonists, bitter taste receptors, and selective phosphodiesterase (PDE) inhibitors.
  • Bronchodilators are increasingly utilized in combination therapies for COPD management.

Conclusions:

  • Emerging bronchodilators offer potential advancements in COPD treatment through improved efficacy, safety, and novel mechanisms of action.
  • Combination therapies involving existing and novel bronchodilators are becoming a cornerstone of COPD management.