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Actinomyces cardiffensis septicemia: a case report.
Jeong Youn Seo1, Joon-Sup Yeom, Kwan Soo Ko
1Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
Diagnostic Microbiology and Infectious Disease
|March 27, 2012
Summary
This case report details a rare Actinomyces cardiffensis bacteremia in a 67-year-old man. Effective treatment involved ceftriaxone and amoxicillin, leading to rapid patient recovery.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Clinical Bacteriology
Background:
- Actinomyces cardiffensis is a recently identified anaerobic, Gram-positive bacterium.
- Actinomyces species are known to cause various infections, though A. cardiffensis is rarely reported in clinical settings.
Observation:
- A 67-year-old male presented with prolonged fever and headache.
- Blood cultures identified an Actinomyces species, confirmed as A. cardiffensis via 16S rRNA gene sequencing.
- Computed tomography revealed hepatic and pulmonary abscesses.
Findings:
- The patient experienced rapid clinical improvement following a 3-week course of intravenous ceftriaxone.
- Subsequent oral amoxicillin completed the antibiotic regimen.
- Successful treatment of A. cardiffensis bacteremia with abscesses was achieved.
Implications:
- This case highlights the importance of considering A. cardiffensis in the differential diagnosis of Gram-positive rod bacteremia, especially with abscess formation.
- Prompt identification and appropriate antibiotic therapy are crucial for favorable outcomes.
- Further research into the pathogenicity and optimal treatment strategies for A. cardiffensis infections is warranted.
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