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Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
Published on: July 10, 2014
Chitosan whiskers from shrimp shells incorporated into dimethacrylate-based dental resin sealant
Ekamon Mahapoka1, Pratanporn Arirachakaran, Anyarat Watthanaphanit
1Department of Operative Dentistry, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand.
Abstract:
A resin-based sealant containing chitosan whiskers was developed for use as a pit and fissure sealer. Chitosan whiskers were synthesized and then characterized using Fourier transform infrared spectrometry and transmission electron microscopy. The whiskers were next incorporated into dimethacrylate monomer at various ratios by weight and subsequently analyzed for their antimicrobial and physical properties. The dimethacrylate-based sealant containing chitosan whiskers had a greater antimicrobial activity than control sealant and they were comparable with antimicrobial commercial resin sealants. The inclusion of the whiskers did not reduce the curing depth or degree of double bond conversion and the reduction in hardness was minimal. In conclusion, a resin-based sealant containing chitosan whiskers can be considered an effective antimicrobial pit and fissure sealant.
