Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ocular atopy and mycotic keratitis.

R B Vajpayee1, S K Gupta, U Bareja

  • 1Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi.

Annals of Ophthalmology
|October 1, 1990
PubMed
Summary

Ocular atopy, or allergic conjunctivitis, was linked to fungal corneal ulcers in a study. Many patients used corticosteroids before infection, and silver sulfadiazine showed 77.8% efficacy against fungal keratitis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparison of Chemotherapy Combined with Percutaneous Electroporation and Chemotherapy Alone in the Management of Locally Advanced Gallbladder Carcinoma (GBC): A Study Protocol.

Cardiovascular and interventional radiology·2024
Same author

DNA methylation variations are required for epithelial-to-mesenchymal transition induced by cancer-associated fibroblasts in prostate cancer cells.

Oncogene·2017
Same author

A Five-Year Study of Intrapleural Fibrinolytic Therapy in Loculated Pleural Collections.

The Indian journal of chest diseases & allied sciences·2017
Same author

Adenosine A1 receptor antagonist mitigates deleterious effects of sleep deprivation on adult neurogenesis and spatial reference memory in rats.

Neuroscience·2016
Same author

Building operational research capacity in the Pacific.

Public health action·2015
Same author

Pre-treatment loss to follow-up among smear-positive pulmonary tuberculosis cases: a 10-year audit of national data from Fiji.

Public health action·2015

Area of Science:

  • Ophthalmology
  • Mycology
  • Infectious Diseases

Background:

  • Ocular atopy is a common allergic eye condition.
  • Fungal keratitis (keratomycosis) is a serious corneal infection.
  • Corticosteroid use is a known risk factor for fungal infections.

Purpose of the Study:

  • To investigate the association between ocular atopy and fungal corneal ulcers.
  • To identify common fungal pathogens in keratomycosis.
  • To evaluate the efficacy of silver sulfadiazine in treating fungal keratitis.

Main Methods:

  • Retrospective analysis of 156 patients with fungal corneal ulcers.
  • Assessment for pre-existing allergic conjunctivitis.
  • Fungal isolation and identification using Sabouraud's agar.
  • Treatment with 1% silver sulfadiazine and efficacy evaluation.

Main Results:

  • 26.3% of patients with fungal ulcers had pre-existing allergic conjunctivitis.
  • Fusarium (32.3%) and Aspergillus (29%) were the most common fungi isolated.
  • Silver sulfadiazine achieved an overall efficacy of 77.8% in treating fungal keratitis.
  • Fusarium species showed the highest sensitivity (87.5%) to silver sulfadiazine.

Conclusions:

  • Ocular atopy may be a significant risk factor for developing fungal corneal ulcers.
  • Prompt diagnosis and appropriate antifungal treatment are crucial for managing keratomycosis.
  • Silver sulfadiazine is an effective agent for treating fungal keratitis, particularly infections caused by Fusarium.

Related Experiment Videos