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Related Concept Videos

The Cochlea01:13

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The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
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Related Experiment Video

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A Method to Study Adaptation to Left-Right Reversed Audition
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Published on: October 29, 2018

Audiometric asymmetry and tinnitus laterality.

Betty S Tsai1, Robert W Sweetow, Steven W Cheung

  • 1Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennesee, USA.

The Laryngoscope
|March 27, 2012
PubMed
Summary

An optimal index for predicting tinnitus laterality uses the average interaural threshold difference (aITD) of two adjoining frequencies. A minimum aITD of 15 dB best predicts tinnitus laterality.

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Area of Science:

  • Audiology
  • Neuroscience

Background:

  • Tinnitus laterality is a common symptom.
  • Predicting tinnitus laterality is crucial for understanding its underlying mechanisms and developing targeted therapies.

Purpose of the Study:

  • To identify an optimal audiometric asymmetry index for predicting tinnitus laterality.

Main Methods:

  • Retrospective review of adult tinnitus patients' medical records.
  • Audiometric data, including interaural threshold differences (ITDs) across frequencies, were analyzed.
  • Sensitivity, specificity, and positive predictive value (PPV) were calculated using receiver operating characteristic (ROC) curves to evaluate predictive performance.

Main Results:

  • Indices using two or three frequencies performed better than single-frequency indices.
  • An optimal index was identified using the average interaural threshold difference (aITD) of two adjoining frequencies.
  • A minimum aITD of 15 dB for two adjoining frequencies demonstrated optimal prediction of tinnitus laterality (sensitivity = 0.59, specificity = 0.71, PPV = 0.76).

Conclusions:

  • The optimal audiometric asymmetry index for predicting tinnitus laterality involves a minimum aITD of 15 dB across two adjoining frequencies.
  • This finding can inform the design and interpretation of neuroimaging studies investigating tinnitus.
  • Monaural acoustic tinnitus therapy is suggested for asymmetric hearing loss meeting this criterion.