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The danger of biopsy in fibrodysplasia ossificans progressiva

Xin Zan1, Jie Wang, Chao You

  • 1West China Hospital, Sichuan University, Department of Neurosurgery, No. 37 Guoxue Alley, Chengdu, Sichuan, China. neuroswch@gmail.com

Archives of Disease in Childhood
|March 27, 2012
PubMed
Abstract

No abstract available in PubMed .

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...