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[Intravesical electrostimulation and magnetotherapy in chronic pyelonephritis and cystitis in children with
Insights
Intravesical electrostimulation and adrenal magnetotherapy effectively treat pediatric chronic pyelonephritis and cystitis. This combined therapy significantly reduces neurogenic bladder dysfunction and vesicoureteral reflux symptoms, improving renal blood flow and decreasing recurrence rates.
Area of Science:
- Pediatric Urology
- Nephrology
- Physical Medicine and Rehabilitation
Context:
- Chronic pyelonephritis and cystitis in children can lead to significant morbidity, including neurogenic bladder dysfunction (NDUB) and vesicoureteral reflux (VUR).
- Standard treatments may not fully address the complex urodynamic abnormalities associated with these conditions, necessitating innovative therapeutic approaches.
- Assessing the efficacy of novel physiotherapeutic interventions in conjunction with pharmacological management is crucial for improving patient outcomes.
Purpose:
- To evaluate the effectiveness of intravesical electrostimulation (IVES) combined with adrenal magnetotherapy in treating pediatric patients with chronic pyelonephritis and/or cystitis complicated by NDUB and/or VUR.
- To compare the outcomes of this combined therapy against standard treatment protocols in a control group.
- To assess the impact of the proposed treatment on symptom alleviation, renal hemodynamics, and recurrence rates.
Summary:
- A study involving 38 children (aged 6-14) with chronic pyelonephritis/cystitis, NDUB, and/or VUR investigated the efficacy of IVES and adrenal magnetotherapy alongside standard medication.
- IVES utilized high-frequency current impulses (2.2 kHz) via the INTRASTIM attachment to the AMUS-01-INTRAMAG device.
- The study group showed a 59.5% alleviation of NDUB symptoms (vs. 38.1% in controls) and a 24.3% increase in renal artery blood flow (vs. 10.5% in controls), with a 2.2-fold reduction in recurrences.
Impact:
- The combined pharmacological and physiotherapeutic approach demonstrated significant improvement in NDUB symptom resolution and enhanced renal perfusion in pediatric patients.
- This novel treatment strategy resulted in a substantial decrease in the recurrence rate of chronic pyelonephritis and cystitis, suggesting a more effective management of underlying urodynamic abnormalities.
- The findings support the integration of IVES and adrenal magnetotherapy as a valuable therapeutic option for children suffering from complex urinary tract infections with associated bladder dysfunction and reflux.
Abstract:
The results of the treatment of 38 children (6 boys and 32 girls, age 6-14 years) with chronic pyelonephritis and/or cystitis complicated with neurogenic dysfunction of the urinary bladder (NDUB) and/or vesicoureteral reflux (VUR) of the first-third degree demonstrate efficacy of intravesical electrostimulation (IVES) and adrenal magnetotherapy. IVES was conducted with high-frequency current impulses (2.2 kHz) by means of INTRASTIM attachment to the device AMUS-01-INTRAMAG in the region of the urethrovesical anastomosis via solution of the drugs for instillation. As the result of exposure to both physical factors in the presence of standard medication, NDUB symptoms alleviated (by E.L. Vishnevsky's criteria) by 59.5% against 38.1% in the control group. Dopplerographic examination of renal vessels stated a 24.3% increase in blood flow in the major renal artery in the study group against 10.5% in the control. The proposed complex pharmacological plus physiotherapeutic treatment of chronic pyelonephritis and cystitis in abnormal urodynamics resulted in a 2.2-fold decrease in the number of recurrences compared to the standard treatment.
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