Toscana virus infections in northern Italy: laboratory and clinical evaluation

Caterina Vocale1, Michele Bartoletti, Giada Rossini

  • 1Department of Haematology and Oncology L. and A. Seragnoli, Section of Microbiology, St. Orsola University Hospital, University of Bologna, Bologna, Italy.

Insights

Toscana virus (TOSv) causes aseptic meningitis in Italy. This study found 15% of meningitis cases during summer months were acute Toscana virus disease.

Area of Science:

  • Virology
  • Epidemiology
  • Neurology

Background:

  • Toscana virus (TOSv) is an arthropod-borne virus.
  • It is known to cause meningitis in the Mediterranean basin.
  • Symptoms typically appear during summer months.

Purpose of the Study:

  • To evaluate the prevalence of TOSv in patients with acute aseptic meningitis.
  • To determine the role of TOSv in summer meningitis cases in northern Italy.

Main Methods:

  • A total of 120 patients with acute aseptic meningitis were evaluated.
  • The study period was from July 1 to October 31, 2010.
  • Patients were assessed for TOSv infection during the acute stage.

Main Results:

  • Eighteen out of 120 patients (15%) were diagnosed with acute TOSv disease.
  • This indicates a significant presence of TOSv during the study period.

Conclusions:

  • Toscana virus is a notable cause of acute aseptic meningitis in northern Italy.
  • Public health awareness and diagnostic capabilities for TOSv are important during summer months.

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