[Thermoanalytic techniques for the study of pharmaceutical products]

During the past years, there have been frequent demonstrations that thermoanalytical methods have found wide-spread use in pharmacy. Analysts have developed these techniques in pharmaceutical field in the estimation of impurities, in quality control procedures, in preformulation studies, in the active principle identification, in accelerated stability and in production process optimization. Wide-spread use of thermal methods is devoted to the identification of solid state of drugs (polymorphism, solvate, inclusion compound,...) due to its possible implication on bioavailability or on the stability of a final dosage form. Some examples of thermoanalytical applications are reported.