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Published on: December 15, 2014
Diffusion-weighted imaging of a malignant brenner tumor
Kumiko Kikukawa1, Kazuhiro Kitajima, Tetsuo Maeda
1Department of Radiology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
Summary
This study details a rare ovarian malignant Brenner tumor case. Imaging findings on diffusion-weighted images (DWI) correlated with histologic transitions from benign to malignant components.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Ovarian malignant Brenner tumors are rare neoplasms characterized by a mixture of malignant transitional cell carcinoma and benign/borderline elements.
- Accurate preoperative diagnosis and characterization of tumor components are crucial for appropriate management.
Observation:
- A unique case of ovarian malignant Brenner tumor exhibited distinct signal intensities on T2-weighted and diffusion-weighted imaging (DWI).
- The benign tumor component demonstrated low signal intensity on T2-weighted images.
- The malignant component showed high signal intensity on T2-weighted images and DWI, with a low apparent diffusion coefficient (ADC) value.
Findings:
- Diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) values can differentiate between benign and malignant components within ovarian malignant Brenner tumors.
- The observed imaging characteristics correlated with histologic findings, showing a transition from benign to malignant.
Implications:
- This case highlights the potential utility of advanced MRI sequences, particularly DWI, in the non-invasive characterization of complex ovarian tumors.
- Integrating radiologic findings with histopathology can improve diagnostic accuracy and guide treatment strategies for ovarian malignant Brenner tumors.
