Related Experiment Video
Updated: May 23, 2026
09:04
Measurement of T Cell Alloreactivity Using Imaging Flow Cytometry
Published on: April 19, 2017
Diagnostic challenges in chronic antibody-mediated rejection
Evan A Farkash1, Robert B Colvin
1Department of Pathology, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.
Nature Reviews. Nephrology
|March 28, 2012
Abstract:
Measurement of glomerular and peritubular capillaritis in kidney transplant biopsy samples identifies allograft dysfunction associated with alloantibodies. Sis et al. show that this technique has a higher sensitivity but lower specificity than the current diagnostic criteria using peritubular capillary C4d deposition, and that capillaritis is an independent predictor of progression to graft failure.
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