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Updated: May 23, 2026
Assessment and Characterization of Hyaloid Vessels in Mice
Published on: May 15, 2019
Verification of posterior hyaloid status during pars plana vitrectomy, after preoperative evaluation on optical
Rubina Rahman1, Rishika Chaudhary, Nitin Anand
1Department of Ophthalmology, Calderdale Royal Hospital, Halifax, UK.
Background:
The purpose of the study is to establish the accuracy of optical coherence tomography (OCT) in visualizing the presence or absence of vitreopapillary adhesion.
Methods:
This is a prospective, interventional case series based at Calderdale Royal Hospital and Huddersfield Royal Infirmary, both district general hospitals in the United Kingdom. Fifty consecutive eyes of 50 patients listed for vitrectomy surgery that showed media clear enough to enable adequate visualization of the fundus were included. All patients underwent assessment of posterior hyaloid status by OCT imaging of the optic disk. All OCT images were assessed by two observers, and preoperative OCT data were compared with intraoperative observations. Statistical analysis was performed using the Cohen κ coefficient to measure the interrater agreement.
Results:
There was 100% agreement between Observer 1 and 2. Cohen κ was 0.95 and (95% confidence interval, 0.84-1.05) for agreement between preoperative OCT and intraoperative findings.
Conclusion:
Optical coherence tomography imaging can accurately visualize the vitreopapillary interface. Our results show a strong correlation between OCT and intraoperative findings. The presence of a posterior vitreous detachment would be useful knowledge to the vitreoretinal surgeon in planning surgery and weighing up the risk of developing certain conditions.
