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Updated: May 23, 2026

Microwave-assisted Intramolecular Dehydrogenative Diels-Alder Reactions for the Synthesis of Functionalized Naphthalenes/Solvatochromic Dyes
Published on: April 1, 2013
Synthesis of 1,8-naphthyridines and their application in the development of anionic fluorogenic chemosensors
Celso R Nicoleti1, Diogo N Garcia, Luiz E da Silva
1Departamento de Química, Universidade Regional de Blumenau, FURB, Blumenau, SC, 89010-971, Brazil.
Abstract:
Two 1,8-naphthyridines were synthesized and found to be fluorescent in solution. These compounds were studied in the presence of Cu(+) and Cu(2+) ions and it was verified that the metal causes the quenching of their fluorescence emission, due to the formation of complexes between the naphthyridine and the metal. A displacement assay was carried out in a DMSO-water mixture with the addition of various anions to the solutions of the complexes, and it was observed that these systems have a high capacity to selectively detect cyanide.
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