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Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies
Published on: January 3, 2011
Corneal displacement during tonometry with a noncontact tonometer
Yoshiaki Kiuchi1, Makoto Kaneko, Hideki Mochizuki
1Department of Ophthalmology and Visual Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Hiroshima, 734-8551, Japan. ykiuchi@hiroshima-u.ac.jp
Japanese Journal of Ophthalmology
|March 28, 2012
Summary
Corneal displacement during noncontact tonometry is influenced by intraocular pressure (IOP), age, and sex. Older males with lower IOP experienced greater corneal displacement, as captured by high-speed photography.
Area of Science:
- Ophthalmology
- Biomedical Engineering
Background:
- Noncontact tonometry is a standard method for measuring intraocular pressure (IOP).
- Understanding corneal biomechanics is crucial for accurate IOP measurement.
- Corneal displacement during tonometry can affect measurement accuracy.
Purpose of the Study:
- To quantify corneal displacement during early-phase noncontact tonometry.
- To identify demographic and physiological factors influencing corneal displacement.
Main Methods:
- High-speed photography (5,000 frames/s) captured corneal profiles during tonometry.
- Corneal displacement was measured 13.2 ms after air puff application in 115 healthy volunteers.
- Stepwise multiple linear regression analyzed factors affecting displacement.
Main Results:
- Age, sex, intraocular pressure (IOP), central corneal thickness, anterior chamber depth, and axial length were analyzed.
- Lower IOP, older age, and male sex were significantly associated with greater corneal displacement.
- Individual corneal response to the air puff varies.
Conclusions:
- High-speed photography effectively quantifies corneal displacement during noncontact tonometry.
- Intraocular pressure, age, and sex are key determinants of corneal displacement.
- These findings may refine tonometry interpretation and glaucoma risk assessment.
