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Updated: May 23, 2026

Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
Published on: June 29, 2013
[Comparative study of pathological Doppler and non-stress test in IUGR]
Abstract:
The aim of the study was to evaluate the timing of delivery and the relationship between pathological Doppler ultrasonography and NST in IUGR fetuses. The prospective study included 84 fetuses with ultrasound diagnosis of IUGR and 100 fetuses of normal pregnancy The study group underwent Doppler velocimetry study of UA, MCA, DV and UV twice weekly, AFI twice weekly and NST daily. Apgar score, need of intubation, RDS, IVH, days of NICU hospitalization were available and related to neonatal outcome. Patients were stratified into groups: Preeclampsia with IUGR (Group 1) and IUGR only (group 2). In the group 1 the stillbirth was 3/44 (6,8%), in the group 2 the stillbirth was 8/40 (20%). Sensitivity for NST was 60%, and for Doppler velocimetry of DV was 71%. Specificity for NST was 87%, and for Doppler velocimetry of DV was 90%, respectively. Doppler changes occur first in chronic hypoxia while abnormal NST represent late stage of fetal compromise.
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