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Updated: Aug 5, 2026

Improving 2D and 3D Skin In Vitro Models Using Macromolecular Crowding
Published on: August 22, 2016
[The mechanism of water transport in the epidermis]
Abstract:
Possible mechanisms of water transport through Stratum Corneum (SC) in the process of insensible perspiration are investigated. Electrometric methods developed for measuring water flow density through SC are used. Data showing the reverse osmotic mechanism of water transport through the SC selective membrane are obtained. It is shown that the water flow density through SC controlling the evaporation rate from the skin surface in the process of insensible perspiration depends upon the skin capillary pressure.
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