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Related Experiment Video

Updated: May 23, 2026

A Technique for Subcutaneous Abdominal Adipose Tissue Biopsy via a Non-diathermy Method
09:01

A Technique for Subcutaneous Abdominal Adipose Tissue Biopsy via a Non-diathermy Method

Published on: September 30, 2017

New device technologies for subcutaneous fat biopsy.

Lawrence G Kettwich1, Wilmer L Sibbitt, N Suzanne Emil

  • 1School of Medicine, Division of Rheumatology, University of New Mexico Health Sciences Center, Albuquerque, USA.

Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis
|March 29, 2012
PubMed
Summary
This summary is machine-generated.

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New syringe technologies improve subcutaneous fat biopsy, enhancing needle control and patient safety. This facilitates accurate diagnosis for conditions like amyloidosis.

Area of Science:

  • Medical Devices
  • Diagnostic Procedures
  • Histopathology

Background:

  • Subcutaneous fat biopsy is a valuable diagnostic tool for various conditions, including amyloidosis, metabolic disorders, and environmental contaminant exposure.
  • Advancements in biopsy techniques are crucial for improving diagnostic accuracy and patient safety.

Purpose of the Study:

  • To evaluate novel syringe technologies for subcutaneous fat biopsy.
  • To compare the efficacy and safety of a reciprocating procedure device (RPD) mechanical syringe versus a vacuum syringe.

Main Methods:

  • A randomized study involving 10 high-risk individuals compared a 10 ml RPD mechanical syringe with a 60 ml vacuum syringe for subcutaneous fat biopsy.
  • Outcomes assessed included pain (Visual Analogue Scale), tissue adequacy, complications, and diagnostic yield.

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Human Subcutaneous Adipose Tissue Sampling Using a Mini-Liposuction Technique
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Human Subcutaneous Adipose Tissue Sampling Using a Mini-Liposuction Technique

Published on: September 27, 2021

Human Adipose Tissue Micro-fragmentation for Cell Phenotyping and Secretome Characterization
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Human Adipose Tissue Micro-fragmentation for Cell Phenotyping and Secretome Characterization

Published on: October 20, 2019

Related Experiment Videos

Last Updated: May 23, 2026

A Technique for Subcutaneous Abdominal Adipose Tissue Biopsy via a Non-diathermy Method
09:01

A Technique for Subcutaneous Abdominal Adipose Tissue Biopsy via a Non-diathermy Method

Published on: September 30, 2017

Human Subcutaneous Adipose Tissue Sampling Using a Mini-Liposuction Technique
08:59

Human Subcutaneous Adipose Tissue Sampling Using a Mini-Liposuction Technique

Published on: September 27, 2021

Human Adipose Tissue Micro-fragmentation for Cell Phenotyping and Secretome Characterization
09:14

Human Adipose Tissue Micro-fragmentation for Cell Phenotyping and Secretome Characterization

Published on: October 20, 2019

  • Operator control was quantitatively measured using the linear displacement method.

    • Main Results:

    • Both mechanical and vacuum syringes yielded adequate fat samples without complications.
    • Both devices significantly improved needle control compared to conventional syringes, reducing unintended penetration.
    • High-quality biopsies suitable for microhistological examination were obtained, leading to diagnoses such as primary AL amyloidosis.

    Conclusions:

    • Novel aspiration syringe technologies facilitate subcutaneous fat biopsy with improved needle control.
    • These advancements enhance patient safety and diagnostic capabilities in fat biopsy procedures.