The management of early Hodgkin's disease

Hodgkin's disease has provided a focus of academic attention for haematologists, radiotherapists and oncologists over the last 20 years but nevertheless there is considerable controversy over the management especially of early presentations. Options include performing a staging laparotomy and splenectomy with radiotherapy for pathological stage I and II disease, clinical staging with combined chemotherapy and radiotherapy, clinical staging with either extensive radiotherapy or with limited radiotherapy and close surveillance, or finally, clinical staging and treatment with chemotherapy alone. An appropriate management decision depends upon an assessment of the disease and also on the impact of treatment side-effects on the individual patient.